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Year : 2022  |  Volume : 1  |  Issue : 3  |  Page : 75-78

Clinical course of a case of elizabethkingia meningoseptica in a critical neonate at a tertiary care hospital in Saudi Arabia

1 King Abdul-Aziz Medical City, Ministry of National Guard, Health Affairs; King Saud Bin Abdul-Aziz University for Health Science, Riyadh, Saudi Arabia
2 Department of Internal Medicine, Prince Sultan Military Medical City, Riyadh, Saudi Arabia
3 College of Pharmacy, Alfaisal University, Riyadh, Saudi Arabia
4 Neonatal Intensive Care Unit, King Abdulaziz Medical City, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia

Correspondence Address:
Dr. Faisal Aqeel AlSehli
King Abdul-Aziz Medical City, Ministry of National Guard, Health Affairs, PO Box 22490, Riyadh 11426
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sjcp.sjcp_11_22

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Case Report: In this paper we discuss the clinical course of a 25-week gestational age preterm neonate who suffered with multiple comorbidities atop of an E. meningoseptica infection causing meningitis and hydrocephalus. A multitude of antibiotics were administered to the child, such as vancomycin, ciprofloxacin, trimethoprim-sulfamethoxazole, and rifampicin. However, the pathogen either had prior resistance to the agents or newly developed resistance along the disease course. After many trials of antibiotics, the usage of ceftazidime/avibactam and moxifloxacin dual therapy induced clinical and microbiological eradication of the pathogen. Objective: This case report aims to discuss the multidrug approach used to treat a preterm neonates Elizabethkingia Meningoseptica infection in a Tertiary Care Hospital in Saudi Arabia. Conclusion: E. meningoseptica is an uncommon infectious agent which can cause meningitis and even sepsis that is difficult to treat due to its multidrug resistance phenotype. Continuous reviews of new case reports on successful attempts of treating E. meningoseptica are paramount to maintaining updated therapy options for newly encountered cases in day-to-day practice in the neonatal intensive care unit (NICU).

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